ITP OpenIR  > 理论物理所科研产出  > SCI论文
Chen, H; Zhou, X; Ou-Yang, ZC; Chen, H , Tsing Hua Univ, Ctr Adv Study, Beijing 100084, Peoples R China.
Difference between "proteinlike" and "nonproteinlike" heteropolymers
发表期刊PHYSICAL REVIEW E
关键词Simple-model Sequences Enumeration Transition Simulation Stability Dynamics Fold
摘要Based on a simple two-dimensional (2D) hydrophobic-polar (H-P) lattice model, properties of amino acid chains are studied by enumeration and Monte-Carlo simulation methods. Among them some chains with Large average energy gap ((E-g) over bar) are thought to be "proteinlike" while the others are "nonproteinlike." The large (E-g) over bar between the low excited conformations and the native conformation guarantees not only the thermodynamic stability of protein but also its fast-folding property. The phase transition from molten globule to the native conformation for the "proteinlike" polymer is found to be of first order, while that for the ''nonproteinlike'' polymer is not. Some properties of chains as a function of (E-g) over bar shows that the transition from "nonproteinlike" to "proteinlike" heteropolymers is continuous. The simulation of folding at different temperature indicates that the main reason why some polymers fold slowly to its native conformation is their low folding temperature which makes the effective energy barrier (E-b/T-f) much higher than "proteinlike" chains.
2001
ISSN1063-651X
卷号63期号:3页码:-
学科领域Physics
收录类别SCI
引用统计
被引频次:10[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.itp.ac.cn/handle/311006/12807
专题理论物理所科研产出_SCI论文
通讯作者Chen, H , Tsing Hua Univ, Ctr Adv Study, Beijing 100084, Peoples R China.
推荐引用方式
GB/T 7714
Chen, H,Zhou, X,Ou-Yang, ZC,et al. Difference between "proteinlike" and "nonproteinlike" heteropolymers[J]. PHYSICAL REVIEW E,2001,63(3):-.
APA Chen, H,Zhou, X,Ou-Yang, ZC,&Chen, H , Tsing Hua Univ, Ctr Adv Study, Beijing 100084, Peoples R China..(2001).Difference between "proteinlike" and "nonproteinlike" heteropolymers.PHYSICAL REVIEW E,63(3),-.
MLA Chen, H,et al."Difference between "proteinlike" and "nonproteinlike" heteropolymers".PHYSICAL REVIEW E 63.3(2001):-.
条目包含的文件
文件名称/大小 文献类型 版本类型 开放类型 使用许可
Difference between p(118KB) 开放获取使用许可请求全文
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Chen, H]的文章
[Zhou, X]的文章
[Ou-Yang, ZC]的文章
百度学术
百度学术中相似的文章
[Chen, H]的文章
[Zhou, X]的文章
[Ou-Yang, ZC]的文章
必应学术
必应学术中相似的文章
[Chen, H]的文章
[Zhou, X]的文章
[Ou-Yang, ZC]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。