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Zhou, HJ; Zhang, Y; Ou-Yang, ZC; Zhou, HJ , Max Planck Inst Colloids & Interfaces, D-14424 Potsdam, Germany.
Stretch-induced hairpin-coil transitions in designed polynucleotide chains
Source PublicationPHYSICAL REVIEW LETTERS
KeywordSecondary Structure Dna-molecules Stranded-dna Denaturation Separation Mechanics Model
AbstractThr structural property of a poly(dG-dC) or poly(dft-dr) nucleotide is investigated. At low force and room temperatures, the polymer takes on compact hairpin structures. An abrupt transition From hairpin to random coil occurs at certain critical forces, its high cooperativity is related to the unfavorable formation of hairpin and other kinds of looped structures. It is hence necessary to consider the enthalpic effects of single-stranded loops in realistic models of RNA folding. A possible new way to obtain the statistical weights Of elementary nucleotide arrangements is by single-macromolecular mechanical measurements on specifically designed polynucleotides.
2001
ISSN0031-9007
Volume86Issue:2Pages:356-359
Subject AreaPhysics
Indexed BySCI
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Document Type期刊论文
Identifierhttp://ir.itp.ac.cn/handle/311006/12835
Collection理论物理所科研产出_SCI论文
Corresponding AuthorZhou, HJ , Max Planck Inst Colloids & Interfaces, D-14424 Potsdam, Germany.
Recommended Citation
GB/T 7714
Zhou, HJ,Zhang, Y,Ou-Yang, ZC,et al. Stretch-induced hairpin-coil transitions in designed polynucleotide chains[J]. PHYSICAL REVIEW LETTERS,2001,86(2):356-359.
APA Zhou, HJ,Zhang, Y,Ou-Yang, ZC,&Zhou, HJ , Max Planck Inst Colloids & Interfaces, D-14424 Potsdam, Germany..(2001).Stretch-induced hairpin-coil transitions in designed polynucleotide chains.PHYSICAL REVIEW LETTERS,86(2),356-359.
MLA Zhou, HJ,et al."Stretch-induced hairpin-coil transitions in designed polynucleotide chains".PHYSICAL REVIEW LETTERS 86.2(2001):356-359.
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