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题名: Stretch-induced hairpin-coil transitions in designed polynucleotide chains
作者: Zhou, HJ ;  Zhang, Y ;  Ou-Yang, ZC
刊名: PHYSICAL REVIEW LETTERS
出版日期: 2001
卷号: 86, 期号:2, 页码:356-359
关键词: SECONDARY STRUCTURE ;  DNA-MOLECULES ;  STRANDED-DNA ;  DENATURATION ;  SEPARATION ;  MECHANICS ;  MODEL
学科分类: Physics
通讯作者: Zhou, HJ , Max Planck Inst Colloids & Interfaces, D-14424 Potsdam, Germany.
部门归属: Chinese Acad Sci, Inst Theoret Phys, Beijing 100080, Peoples R China
英文摘要: Thr structural property of a poly(dG-dC) or poly(dft-dr) nucleotide is investigated. At low force and room temperatures, the polymer takes on compact hairpin structures. An abrupt transition From hairpin to random coil occurs at certain critical forces, its high cooperativity is related to the unfavorable formation of hairpin and other kinds of looped structures. It is hence necessary to consider the enthalpic effects of single-stranded loops in realistic models of RNA folding. A possible new way to obtain the statistical weights Of elementary nucleotide arrangements is by single-macromolecular mechanical measurements on specifically designed polynucleotides.
收录类别: SCI
原文出处: 查看原文
WOS记录号: WOS:000166231400043
Citation statistics: 
内容类型: 期刊论文
URI标识: http://ir.itp.ac.cn/handle/311006/12835
Appears in Collections:理论物理所1978-2010年知识产出_期刊论文

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Recommended Citation:
Zhou, HJ,Zhang, Y,Ou-Yang, ZC. Stretch-induced hairpin-coil transitions in designed polynucleotide chains[J]. PHYSICAL REVIEW LETTERS,2001,86(2):356-359.
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