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题名: Mean-field HP model, designability and alpha-helices in protein structures
作者: Shih, CT ;  Su, ZY ;  Gwan, JF ;  Hao, BL ;  Hsieh, CH ;  Lee, HC
刊名: PHYSICAL REVIEW LETTERS
出版日期: 2000
卷号: 84, 期号:2, 页码:386-389
关键词: FOLDING FUNNELS ;  STABILITY ;  POTENTIALS ;  MECHANISM ;  CHAINS
学科分类: Physics
通讯作者: Shih, CT , Natl Ctr High Performance Comp, Hsinchu, Taiwan.
部门归属: Natl Ctr High Performance Comp, Hsinchu, Taiwan; Acad Sinica, Inst Theoret Phys, Beijing 100080, Peoples R China; Natl Ctr Theoret Sci, Hsinchu, Taiwan; Natl Cent Univ, Dept Phys, Chungli 32054, Taiwan; Natl Cent Univ, Ctr Complex Syst, Chungli 32054, Taiwan
英文摘要: Analysis of the geometric properties of a mean-field HP model on a square lattice for protein structure shows that structures with a large number of switchbacks between surface and core sites are chosen favorably by peptides as unique ground slates. Global comparison of model (binary) peptide sequences with concatenated (binary) protein sequences listed in the Protein Data Bank and the Dali Domain Dictionary indicates that the highest correlation occurs between model peptides choosing the favored structures and those portions of protein sequences containing alpha helices.
收录类别: SCI
原文出处: 查看原文
WOS记录号: WOS:000084661500045
Citation statistics: 
内容类型: 期刊论文
URI标识: http://ir.itp.ac.cn/handle/311006/13029
Appears in Collections:理论物理所1978-2010年知识产出_期刊论文

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Recommended Citation:
Shih, CT,Su, ZY,Gwan, JF,et al. Mean-field HP model, designability and alpha-helices in protein structures[J]. PHYSICAL REVIEW LETTERS,2000,84(2):386-389.
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文件名: Mean-Field HP Model, Designability and Alpha-Helices in Protein Structures.pdf
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