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In-phase implies large likelihood for independent codon model: distinguishing coding from non-coding sequences
Zheng, WM; Wu, F; Zheng, WM , Acad Sinica, Inst Theoret Phys, POB 2735, Beijing 100080, Peoples R China.
2003
发表期刊JOURNAL OF THEORETICAL BIOLOGY
ISSN0022-5193
卷号223期号:2页码:199-203
摘要It is proven that under the independent codon model, the likelihood of a DNA coding sequence read according to the correct frame is asymptotically larger than that read with an incorrect frame. Based on this proposition, a single set of probabilities of the codon usage is enough for discriminating the six frames of coding sequences under the independent codon model. The direct coding sequence of Escherichia coli genome is taken as an example to examine the codon independency by using the mutual information and chi(2) analysis. The contrast between the coding frame and the two offset frames is evident. A self-learning approach for generating training set is proposed to estimate probability parameters. (C) 2003 Elsevier Rience Ltd. All rights reserved.
部门归属Acad Sinica, Inst Theoret Phys, Beijing 100080, Peoples R China
关键词Identification Regions
学科领域Physics
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收录类别SCI
WOS记录号WOS:000184078400006
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被引频次:2[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.itp.ac.cn/handle/311006/13257
专题理论物理所1978-2010年知识产出
通讯作者Zheng, WM , Acad Sinica, Inst Theoret Phys, POB 2735, Beijing 100080, Peoples R China.
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Zheng, WM,Wu, F,Zheng, WM , Acad Sinica, Inst Theoret Phys, POB 2735, Beijing 100080, Peoples R China.. In-phase implies large likelihood for independent codon model: distinguishing coding from non-coding sequences[J]. JOURNAL OF THEORETICAL BIOLOGY,2003,223(2):199-203.
APA Zheng, WM,Wu, F,&Zheng, WM , Acad Sinica, Inst Theoret Phys, POB 2735, Beijing 100080, Peoples R China..(2003).In-phase implies large likelihood for independent codon model: distinguishing coding from non-coding sequences.JOURNAL OF THEORETICAL BIOLOGY,223(2),199-203.
MLA Zheng, WM,et al."In-phase implies large likelihood for independent codon model: distinguishing coding from non-coding sequences".JOURNAL OF THEORETICAL BIOLOGY 223.2(2003):199-203.
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