Zheng, WM , Acad Sinica, Inst Theoret Phys, POB 2735, Beijing 100080, Peoples R China.
部门归属:
Acad Sinica, Inst Theoret Phys, Beijing 100080, Peoples R China; Beijing Genom Inst, Beijing 101300, Peoples R China
英文摘要:
Weight matrix models for signal sequence motif are simple. A main limitation of the models is the assumption of independence between positions. Signal enhancement is achieved by taking the total likelihood as the objective function for maximization to cluster sequences into groups with different patterns. As an example, the initial and terminal signals for translation in rice genome are examined.
