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Wu, F; Zheng, WM; Wu, F , Peking Univ, Dept Phys, Beijing 100871, Peoples R China.
Which are more random: Coding or noncoding DNA sequences?
Source PublicationCOMMUNICATIONS IN THEORETICAL PHYSICS
KeywordMutual Information
AbstractEvidence seems to show that coding DNA is more random than noncoding DNA, but other conflicting evidence also exists. Based on the third-base degeneracy of codons, we regard the third position of codons as a 'noisy' position. By deleting one fixed position of non-overlapping triplets in a given sequence, three masked sequences may be deduced from the sequence. We have investigated the block-to-site mutual information functions of coding and noncoding sequences in yeast without and with the masking. Characteristics that distinguish coding from noncoding DNA have been found, It is observed that the strong correlations in the coding regions may be blocked by the third base of codons, and the proper masking can extract the correlations. Distribution of dimeric tandem repeats of unmasked sequences is also compared with that of masked sequences.
2002
ISSN0253-6102
Volume37Issue:5Pages:637-640
Subject AreaPhysics
Indexed BySCI
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Document Type期刊论文
Identifierhttp://ir.itp.ac.cn/handle/311006/13518
Collection理论物理所科研产出_SCI论文
Corresponding AuthorWu, F , Peking Univ, Dept Phys, Beijing 100871, Peoples R China.
Recommended Citation
GB/T 7714
Wu, F,Zheng, WM,Wu, F , Peking Univ, Dept Phys, Beijing 100871, Peoples R China.. Which are more random: Coding or noncoding DNA sequences?[J]. COMMUNICATIONS IN THEORETICAL PHYSICS,2002,37(5):637-640.
APA Wu, F,Zheng, WM,&Wu, F , Peking Univ, Dept Phys, Beijing 100871, Peoples R China..(2002).Which are more random: Coding or noncoding DNA sequences?.COMMUNICATIONS IN THEORETICAL PHYSICS,37(5),637-640.
MLA Wu, F,et al."Which are more random: Coding or noncoding DNA sequences?".COMMUNICATIONS IN THEORETICAL PHYSICS 37.5(2002):637-640.
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