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题名: Which are more random: Coding or noncoding DNA sequences?
作者: Wu, F ;  Zheng, WM
刊名: COMMUNICATIONS IN THEORETICAL PHYSICS
出版日期: 2002
卷号: 37, 期号:5, 页码:637-640
关键词: MUTUAL INFORMATION
学科分类: Physics
通讯作者: Wu, F , Peking Univ, Dept Phys, Beijing 100871, Peoples R China.
部门归属: Peking Univ, Dept Phys, Beijing 100871, Peoples R China; Acad Sinica, Inst Theoret Phys, Beijing 100080, Peoples R China
英文摘要: Evidence seems to show that coding DNA is more random than noncoding DNA, but other conflicting evidence also exists. Based on the third-base degeneracy of codons, we regard the third position of codons as a 'noisy' position. By deleting one fixed position of non-overlapping triplets in a given sequence, three masked sequences may be deduced from the sequence. We have investigated the block-to-site mutual information functions of coding and noncoding sequences in yeast without and with the masking. Characteristics that distinguish coding from noncoding DNA have been found, It is observed that the strong correlations in the coding regions may be blocked by the third base of codons, and the proper masking can extract the correlations. Distribution of dimeric tandem repeats of unmasked sequences is also compared with that of masked sequences.
收录类别: SCI
原文出处: 查看原文
WOS记录号: WOS:000175979800027
Citation statistics: 
内容类型: 期刊论文
URI标识: http://ir.itp.ac.cn/handle/311006/13518
Appears in Collections:理论物理所1978-2010年知识产出_期刊论文

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Recommended Citation:
Wu, F,Zheng, WM. Which are more random: Coding or noncoding DNA sequences?[J]. COMMUNICATIONS IN THEORETICAL PHYSICS,2002,37(5):637-640.
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