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Which are more random: Coding or noncoding DNA sequences?
Wu, F; Zheng, WM; Wu, F , Peking Univ, Dept Phys, Beijing 100871, Peoples R China.
2002
发表期刊COMMUNICATIONS IN THEORETICAL PHYSICS
ISSN0253-6102
卷号37期号:5页码:637-640
摘要Evidence seems to show that coding DNA is more random than noncoding DNA, but other conflicting evidence also exists. Based on the third-base degeneracy of codons, we regard the third position of codons as a 'noisy' position. By deleting one fixed position of non-overlapping triplets in a given sequence, three masked sequences may be deduced from the sequence. We have investigated the block-to-site mutual information functions of coding and noncoding sequences in yeast without and with the masking. Characteristics that distinguish coding from noncoding DNA have been found, It is observed that the strong correlations in the coding regions may be blocked by the third base of codons, and the proper masking can extract the correlations. Distribution of dimeric tandem repeats of unmasked sequences is also compared with that of masked sequences.
部门归属Peking Univ, Dept Phys, Beijing 100871, Peoples R China; Acad Sinica, Inst Theoret Phys, Beijing 100080, Peoples R China
关键词Mutual Information
学科领域Physics
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收录类别SCI
WOS记录号WOS:000175979800027
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文献类型期刊论文
条目标识符http://ir.itp.ac.cn/handle/311006/13518
专题理论物理所1978-2010年知识产出
通讯作者Wu, F , Peking Univ, Dept Phys, Beijing 100871, Peoples R China.
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Wu, F,Zheng, WM,Wu, F , Peking Univ, Dept Phys, Beijing 100871, Peoples R China.. Which are more random: Coding or noncoding DNA sequences?[J]. COMMUNICATIONS IN THEORETICAL PHYSICS,2002,37(5):637-640.
APA Wu, F,Zheng, WM,&Wu, F , Peking Univ, Dept Phys, Beijing 100871, Peoples R China..(2002).Which are more random: Coding or noncoding DNA sequences?.COMMUNICATIONS IN THEORETICAL PHYSICS,37(5),637-640.
MLA Wu, F,et al."Which are more random: Coding or noncoding DNA sequences?".COMMUNICATIONS IN THEORETICAL PHYSICS 37.5(2002):637-640.
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