ITP OpenIR  > 理论物理所科研产出  > SCI论文
Wang, B; Wang, B , Acad Sinica, Inst Theoret Phys, POB 2735, Beijing 100080, Peoples R China.
Limitations of compositional approach to identifying horizontally transferred genes
Source PublicationJOURNAL OF MOLECULAR EVOLUTION
KeywordEscherichia-coli Genome Bacterial Hyperthermophiles Common Ancestry Archaeal Exchange Sequences Tree Life Divergence Evolution
AbstractGenes with atypical G+C content and pattern of codon usage in a certain genome are possibly of exotic origin, and this idea has been applied to identify horizontal events. In this way, it was postulated that a total of 755 genes in the E. coli genome are relics of horizontal events after the divergence of E. coli from the Salmonella lineage 100 million years ago (Lawrence and Ochman. 1998). In this paper we propose a new way to study sequence composition more thoroughly. We found that although the 755 genes differ in composition from other genes in the E. coli genome. the difference is minor. If we accepted that these genes are horizontally transferred. then (1) it would be more likely that they were transferred from genomes evolutionarily closely related to E. coli: but (2) the dating method used by Lawrence and Ochman (1997, 1998) largely underestimated the average age of introduced sequences in the E. coli genome, in particular, most of the 755 genes should be introduced into E. coli before, instead of after, the divergence of E. coli from the Salmonella lineage. Our study reveals that atypical G+C content and pattern of codon usage are not reliable indicators of horizontal gene transfer events.
2001
ISSN0022-2844
Volume53Issue:3Pages:244-250
Subject AreaPhysics
Indexed BySCI
Citation statistics
Document Type期刊论文
Identifierhttp://ir.itp.ac.cn/handle/311006/13673
Collection理论物理所科研产出_SCI论文
Corresponding AuthorWang, B , Acad Sinica, Inst Theoret Phys, POB 2735, Beijing 100080, Peoples R China.
Recommended Citation
GB/T 7714
Wang, B,Wang, B , Acad Sinica, Inst Theoret Phys, POB 2735, Beijing 100080, Peoples R China.. Limitations of compositional approach to identifying horizontally transferred genes[J]. JOURNAL OF MOLECULAR EVOLUTION,2001,53(3):244-250.
APA Wang, B,&Wang, B , Acad Sinica, Inst Theoret Phys, POB 2735, Beijing 100080, Peoples R China..(2001).Limitations of compositional approach to identifying horizontally transferred genes.JOURNAL OF MOLECULAR EVOLUTION,53(3),244-250.
MLA Wang, B,et al."Limitations of compositional approach to identifying horizontally transferred genes".JOURNAL OF MOLECULAR EVOLUTION 53.3(2001):244-250.
Files in This Item:
File Name/Size DocType Version Access License
Limitations of Compo(399KB) 开放获取LicenseApplication Full Text
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Wang, B]'s Articles
[Wang, B , Acad Sinica, Inst Theoret Phys, POB 2735, Beijing 100080, Peoples R China.]'s Articles
Baidu academic
Similar articles in Baidu academic
[Wang, B]'s Articles
[Wang, B , Acad Sinica, Inst Theoret Phys, POB 2735, Beijing 100080, Peoples R China.]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Wang, B]'s Articles
[Wang, B , Acad Sinica, Inst Theoret Phys, POB 2735, Beijing 100080, Peoples R China.]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.