中国科学院理论物理研究所机构知识库
Advanced  
ITP OpenIR  > 理论物理所1978-2010年知识产出  > 期刊论文
题名: Limitations of compositional approach to identifying horizontally transferred genes
作者: Wang, B
刊名: JOURNAL OF MOLECULAR EVOLUTION
出版日期: 2001
卷号: 53, 期号:3, 页码:244-250
关键词: ESCHERICHIA-COLI GENOME ;  BACTERIAL HYPERTHERMOPHILES ;  COMMON ANCESTRY ;  ARCHAEAL ;  EXCHANGE ;  SEQUENCES ;  TREE ;  LIFE ;  DIVERGENCE ;  EVOLUTION
学科分类: Physics
通讯作者: Wang, B , Acad Sinica, Inst Theoret Phys, POB 2735, Beijing 100080, Peoples R China.
部门归属: Acad Sinica, Inst Theoret Phys, Beijing 100080, Peoples R China; Inst Computat Math & Sci Engn Comp, State Key Lab Sci & Engn Comp, Beijing 100080, Peoples R China
英文摘要: Genes with atypical G+C content and pattern of codon usage in a certain genome are possibly of exotic origin, and this idea has been applied to identify horizontal events. In this way, it was postulated that a total of 755 genes in the E. coli genome are relics of horizontal events after the divergence of E. coli from the Salmonella lineage 100 million years ago (Lawrence and Ochman. 1998). In this paper we propose a new way to study sequence composition more thoroughly. We found that although the 755 genes differ in composition from other genes in the E. coli genome. the difference is minor. If we accepted that these genes are horizontally transferred. then (1) it would be more likely that they were transferred from genomes evolutionarily closely related to E. coli: but (2) the dating method used by Lawrence and Ochman (1997, 1998) largely underestimated the average age of introduced sequences in the E. coli genome, in particular, most of the 755 genes should be introduced into E. coli before, instead of after, the divergence of E. coli from the Salmonella lineage. Our study reveals that atypical G+C content and pattern of codon usage are not reliable indicators of horizontal gene transfer events.
收录类别: SCI
原文出处: 查看原文
WOS记录号: WOS:000170659000009
Citation statistics: 
内容类型: 期刊论文
URI标识: http://ir.itp.ac.cn/handle/311006/13673
Appears in Collections:理论物理所1978-2010年知识产出_期刊论文

Files in This Item: Download All
File Name/ File Size Content Type Version Access License
Limitations of Compositional Approach to Identifying Horizontally Transferred Genes.pdf(399KB)----开放获取View Download

Recommended Citation:
Wang, B. Limitations of compositional approach to identifying horizontally transferred genes[J]. JOURNAL OF MOLECULAR EVOLUTION,2001,53(3):244-250.
Service
 Recommend this item
 Sava as my favorate item
 Show this item's statistics
 Export Endnote File
Google Scholar
 Similar articles in Google Scholar
 [Wang, B]'s Articles
CSDL cross search
 Similar articles in CSDL Cross Search
 [Wang, B]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
  Add to CiteULike  Add to Connotea  Add to Del.icio.us  Add to Digg  Add to Reddit 
文件名: Limitations of Compositional Approach to Identifying Horizontally Transferred Genes.pdf
格式: Adobe PDF
此文件暂不支持浏览
所有评论 (0)
暂无评论
 
评注功能仅针对注册用户开放,请您登录
您对该条目有什么异议,请填写以下表单,管理员会尽快联系您。
内 容:
Email:  *
单位:
验证码:   刷新
您在IR的使用过程中有什么好的想法或者建议可以反馈给我们。
标 题:
 *
内 容:
Email:  *
验证码:   刷新

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Copyright © 2007-2017  中国科学院理论物理研究所 - Feedback
Powered by CSpace