Unfolding single RNA molecules by mechanical force: A stochastic kinetic method

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	Unfolding single RNA molecules by mechanical force: A stochastic kinetic method
	Liu, F; Ou-Yang, ZC; Liu, F , Tsing Hua Univ, Ctr Adv Study, Beijing 100084, Peoples R China.
	2004
发表期刊	PHYSICAL REVIEW E
ISSN	1539-3755
卷号	70 期号:4 页码:-
摘要	Using simple polymer elastic theory and known RNA free energies, we study the single RNA folding and unfolding on the secondary structure level under mechanical constant force by stochastic kinetic simulation. As a primary application, this method is used to simulate the experiment performed by Liphardt et al. [Science 292, 733 (2001)]. The extension-force curves in equilibrium and kinetic reaction rate constants for folding and unfolding are calculated. Our results show that the agreement between simulation and experimental measurements is satisfactory.
部门归属	Tsing Hua Univ, Ctr Adv Study, Beijing 100084, Peoples R China; Chinese Acad Sci, Inst Theoret Phys, Beijing 100080, Peoples R China
关键词	Titin Immunoglobulin Domains Secondary Structure Stranded-dna Protein Elasticity Simulation Algorithm Dynamics Models
学科领域	Physics
URL	查看原文
收录类别	SCI
WOS记录号	WOS:000225689500006
引用统计	被引频次：2[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.itp.ac.cn/handle/311006/13995
专题	理论物理所SCI论文
通讯作者	Liu, F , Tsing Hua Univ, Ctr Adv Study, Beijing 100084, Peoples R China.
推荐引用方式 GB/T 7714	Liu, F,Ou-Yang, ZC,Liu, F , Tsing Hua Univ, Ctr Adv Study, Beijing 100084, Peoples R China.. Unfolding single RNA molecules by mechanical force: A stochastic kinetic method[J]. PHYSICAL REVIEW E,2004,70(4):-.
APA	Liu, F,Ou-Yang, ZC,&Liu, F , Tsing Hua Univ, Ctr Adv Study, Beijing 100084, Peoples R China..(2004).Unfolding single RNA molecules by mechanical force: A stochastic kinetic method.PHYSICAL REVIEW E,70(4),-.
MLA	Liu, F,et al."Unfolding single RNA molecules by mechanical force: A stochastic kinetic method".PHYSICAL REVIEW E 70.4(2004):-.

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