Unfolding single RNA molecules by mechanical force: A stochastic kinetic method

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	Liu, F; Ou-Yang, ZC; Liu, F , Tsing Hua Univ, Ctr Adv Study, Beijing 100084, Peoples R China.
	Unfolding single RNA molecules by mechanical force: A stochastic kinetic method
发表期刊	PHYSICAL REVIEW E
关键词	Titin Immunoglobulin Domains Secondary Structure Stranded-dna Protein Elasticity Simulation Algorithm Dynamics Models
摘要	Using simple polymer elastic theory and known RNA free energies, we study the single RNA folding and unfolding on the secondary structure level under mechanical constant force by stochastic kinetic simulation. As a primary application, this method is used to simulate the experiment performed by Liphardt et al. [Science 292, 733 (2001)]. The extension-force curves in equilibrium and kinetic reaction rate constants for folding and unfolding are calculated. Our results show that the agreement between simulation and experimental measurements is satisfactory.
	2004
ISSN	1539-3755
卷号	70 期号:4 页码:-
学科领域	Physics
收录类别	SCI
引用统计
文献类型	期刊论文
条目标识符	http://ir.itp.ac.cn/handle/311006/13995
专题	理论物理所科研产出_SCI论文
通讯作者	Liu, F , Tsing Hua Univ, Ctr Adv Study, Beijing 100084, Peoples R China.
推荐引用方式 GB/T 7714	Liu, F,Ou-Yang, ZC,Liu, F , Tsing Hua Univ, Ctr Adv Study, Beijing 100084, Peoples R China.. Unfolding single RNA molecules by mechanical force: A stochastic kinetic method[J]. PHYSICAL REVIEW E,2004,70(4):-.
APA	Liu, F,Ou-Yang, ZC,&Liu, F , Tsing Hua Univ, Ctr Adv Study, Beijing 100084, Peoples R China..(2004).Unfolding single RNA molecules by mechanical force: A stochastic kinetic method.PHYSICAL REVIEW E,70(4),-.
MLA	Liu, F,et al."Unfolding single RNA molecules by mechanical force: A stochastic kinetic method".PHYSICAL REVIEW E 70.4(2004):-.

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