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题名: CVTree: a phylogenetic tree reconstruction tool based on whole genomes
作者: Qi, J ;  Luo, H ;  Hao, BL
刊名: NUCLEIC ACIDS RESEARCH
出版日期: 2004
卷号: 32, 期号:0, 页码:W45-W47
关键词: INFORMATION ;  ORIGIN ;  UPDATE
学科分类: Physics
通讯作者: Qi, J , Acad Sinica, Inst Theoret Phys, POB 2735, Beijing 100080, Peoples R China.
部门归属: Acad Sinica, Inst Theoret Phys, Beijing 100080, Peoples R China; Peking Univ, Ctr Bioinformat, Beijing 100871, Peoples R China; Fudan Univ, T Life Res Ctr, Shanghai 200433, Peoples R China
英文摘要: Composition Vector Tree (CVTree) implements a systematic method of inferring evolutionary relatedness of microbial organisms from the oligopeptide content of their complete proteomes (http://cvtree.cbi.pku.edu.cn). Since the first bacterial genomes were sequenced in 1995 there have been several attempts to infer prokaryote phylogeny from complete genomes. Most of them depend on sequence alignment directly or indirectly and, in some cases, need fine-tuning and adjustment. The composition vector method circumvents the ambiguity of choosing the genes for phylogenetic reconstruction and avoids the necessity of aligning sequences of essentially different length and gene content. This new method does not contain 'free' parameter and 'fine-tuning'. A bootstrap test for a phylogenetic tree of 139 organisms has shown the stability of the branchings, which support the small subunit ribosomal RNA (SSU rRNA) tree of life in its overall structure and in many details. It may provide a quick reference in prokaryote phylogenetics whenever the proteome of an organism is available, a situation that will become commonplace in the near future.
收录类别: SCI
原文出处: 查看原文
WOS记录号: WOS:000222273100009
Citation statistics: 
内容类型: 期刊论文
URI标识: http://ir.itp.ac.cn/handle/311006/14052
Appears in Collections:理论物理所1978-2010年知识产出_期刊论文

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Recommended Citation:
Qi, J,Luo, H,Hao, BL. CVTree: a phylogenetic tree reconstruction tool based on whole genomes[J]. NUCLEIC ACIDS RESEARCH,2004,32(0):W45-W47.
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