ITP OpenIR  > 理论物理所2014年知识产出
Dimensions of receptor-ligand complex and the optimal radius of endocytosed virus-like particle
Liu, YH; Chen, YB; Mao, W; Hu, L; Deng, LH; Xu, HQ; Liu, YH (reprint author), Guizhou Univ, Coll Anim Sci, Minist Educ, Key Lab Anim Genet Breeding & Reprod Plateau Mt R, Guiyang 550025, Peoples R China.
2014
发表期刊FRONTIERS OF PHYSICS
ISSN2095-0462
卷号9期号:4页码:519-522
摘要Recent experiments have pointed out that cellular uptake is strongly dependent on the physical dimensions of endocytosed nanoparticles and the optimal radius of endocytosed virus-like particle coated by transferrin is around 50 nm. As the same time, the dimensions of receptor-ligand complex have strong effects on the size-dependent exclusion of proteins in cell environments. Inspired by these experimental results, a continuum elastic model is constructed to resolve the relationship between the dimensions of receptor-ligand complex and the optimal radius of endocytosed virus-like particle. These results demonstrate that the optimal radius of endocytosed virus-like particle depends on the dimensions of receptor-ligand complex and the dimension of receptor-ligand complex reduces the depletion zone.
部门归属[Liu, Yan-Hui ; Xu, Hou-Qiang] Guizhou Univ, Coll Anim Sci, Minist Educ, Key Lab Anim Genet Breeding & Reprod Plateau Mt R, Guiyang 550025, Peoples R China ; [Liu, Yan-Hui ; Chen, Ying-Bing ; Mao, Wei ; Hu, Lin] Guizhou Univ, Coll Sci, Soft Condensed Matter Lab, Guiyang 550025, Peoples R China ; [Liu, Yan-Hui] Chinese Acad Sci, Inst Theoret Phys, State Key Lab Theoret Phys, Beijing 100190, Peoples R China ; [Deng, Lin-Hong] Changzhou Univ, Inst Biomed Engn & Hlth Sci, Changzhou 213164, Peoples R China ; [Deng, Lin-Hong] Chongqing Univ, Bioengn Coll, Key Lab Biorheol Sci & Technol, Minist Educ, Chongqing 400044, Peoples R China
关键词Mediated Endocytosis Cellular Uptake Cells Mechanism Size
学科领域Physics
资助者National Natural Science Foundation of China [11047022, 11204045, 31360215]; Research Foundation from Ministry of Education of China [2012152]; Guizhou Provincial Tracking Key Program of Social Development [SY20123089, SZ20113069]; Natural Science Foundation of Guizhou Province [J20122166]; Visiting Scholar Foundation from the Key Laboratory of Biorheological Science and Technology of Ministry of Education (Chongqing University) ; National Natural Science Foundation of China [11047022, 11204045, 31360215]; Research Foundation from Ministry of Education of China [2012152]; Guizhou Provincial Tracking Key Program of Social Development [SY20123089, SZ20113069]; Natural Science Foundation of Guizhou Province [J20122166]; Visiting Scholar Foundation from the Key Laboratory of Biorheological Science and Technology of Ministry of Education (Chongqing University) ; National Natural Science Foundation of China [11047022, 11204045, 31360215]; Research Foundation from Ministry of Education of China [2012152]; Guizhou Provincial Tracking Key Program of Social Development [SY20123089, SZ20113069]; Natural Science Foundation of Guizhou Province [J20122166]; Visiting Scholar Foundation from the Key Laboratory of Biorheological Science and Technology of Ministry of Education (Chongqing University) ; National Natural Science Foundation of China [11047022, 11204045, 31360215]; Research Foundation from Ministry of Education of China [2012152]; Guizhou Provincial Tracking Key Program of Social Development [SY20123089, SZ20113069]; Natural Science Foundation of Guizhou Province [J20122166]; Visiting Scholar Foundation from the Key Laboratory of Biorheological Science and Technology of Ministry of Education (Chongqing University)
DOI10.1007/s11467-014-0412-6
URL查看原文
收录类别SCI
语种英语
资助者National Natural Science Foundation of China [11047022, 11204045, 31360215]; Research Foundation from Ministry of Education of China [2012152]; Guizhou Provincial Tracking Key Program of Social Development [SY20123089, SZ20113069]; Natural Science Foundation of Guizhou Province [J20122166]; Visiting Scholar Foundation from the Key Laboratory of Biorheological Science and Technology of Ministry of Education (Chongqing University) ; National Natural Science Foundation of China [11047022, 11204045, 31360215]; Research Foundation from Ministry of Education of China [2012152]; Guizhou Provincial Tracking Key Program of Social Development [SY20123089, SZ20113069]; Natural Science Foundation of Guizhou Province [J20122166]; Visiting Scholar Foundation from the Key Laboratory of Biorheological Science and Technology of Ministry of Education (Chongqing University) ; National Natural Science Foundation of China [11047022, 11204045, 31360215]; Research Foundation from Ministry of Education of China [2012152]; Guizhou Provincial Tracking Key Program of Social Development [SY20123089, SZ20113069]; Natural Science Foundation of Guizhou Province [J20122166]; Visiting Scholar Foundation from the Key Laboratory of Biorheological Science and Technology of Ministry of Education (Chongqing University) ; National Natural Science Foundation of China [11047022, 11204045, 31360215]; Research Foundation from Ministry of Education of China [2012152]; Guizhou Provincial Tracking Key Program of Social Development [SY20123089, SZ20113069]; Natural Science Foundation of Guizhou Province [J20122166]; Visiting Scholar Foundation from the Key Laboratory of Biorheological Science and Technology of Ministry of Education (Chongqing University)
WOS记录号WOS:000341429900012
引用统计
被引频次:4[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.itp.ac.cn/handle/311006/15691
专题理论物理所2014年知识产出
通讯作者Liu, YH (reprint author), Guizhou Univ, Coll Anim Sci, Minist Educ, Key Lab Anim Genet Breeding & Reprod Plateau Mt R, Guiyang 550025, Peoples R China.
推荐引用方式
GB/T 7714
Liu, YH,Chen, YB,Mao, W,et al. Dimensions of receptor-ligand complex and the optimal radius of endocytosed virus-like particle[J]. FRONTIERS OF PHYSICS,2014,9(4):519-522.
APA Liu, YH.,Chen, YB.,Mao, W.,Hu, L.,Deng, LH.,...&Liu, YH .(2014).Dimensions of receptor-ligand complex and the optimal radius of endocytosed virus-like particle.FRONTIERS OF PHYSICS,9(4),519-522.
MLA Liu, YH,et al."Dimensions of receptor-ligand complex and the optimal radius of endocytosed virus-like particle".FRONTIERS OF PHYSICS 9.4(2014):519-522.
条目包含的文件
条目无相关文件。
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Liu, YH]的文章
[Chen, YB]的文章
[Mao, W]的文章
百度学术
百度学术中相似的文章
[Liu, YH]的文章
[Chen, YB]的文章
[Mao, W]的文章
必应学术
必应学术中相似的文章
[Liu, YH]的文章
[Chen, YB]的文章
[Mao, W]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。