中国科学院理论物理研究所机构知识库
Advanced  
ITP OpenIR  > 理论物理所2015年知识产出  > 期刊论文
题名: Theoretical studies on sRNA-mediated regulation in bacteria
作者: Chang, XX;  Xu, LF;  Shi, HL
刊名: CHINESE PHYSICS B
出版日期: 2015
卷号: 24, 期号:12, 页码:128703
关键词: sRNA-mediated regulation ;  kinetic model ;  crosstalk
学科分类: Physics
DOI: http://dx.doi.org/10.1088/1674-1056/24/12/128703
通讯作者: Xu, LF (reprint author), Jilin Univ, Dept Phys, Changchun 130012, Peoples R China.
文章类型: Review
英文摘要: Small RNA(sRNA)-mediated post-transcriptional regulation differs from protein-mediated regulation. Through base-pairing, sRNA can regulate the target mRNA in a catalytic or stoichiometric manner. Some theoretical models were built for comparison of the protein-mediated and sRNA-mediated modes in the steady-state behaviors and noise properties. Many experiments demonstrated that a single sRNA can regulate several mRNAs, which causes crosstalk between the targets. Here, we focus on some models in which two target mRNAs are silenced by the same sRNA to discuss their crosstalk features. Additionally, the sequence-function relationship of sRNA and its role in the kinetic process of base-pairing have been highlighted in model building.
类目[WOS]: Physics, Multidisciplinary
关键词[WOS]: STOCHASTIC GENE-EXPRESSION ;  SMALL NONCODING RNAS ;  ESCHERICHIA-COLI ;  MESSENGER-RNA ;  INTRINSIC NOISE ;  HFQ ;  TARGET ;  BINDING ;  RIBOREGULATION ;  ACCESSIBILITY
收录类别: SCI
项目资助者: National Basic Research Program of China [2013CB834100] ;  National Natural Science Foundation of China [11121403, 11274320] ;  Open Project Program of State Key Laboratory of Theoretical Physics, Institute of Theoretical Physics, Chinese Academy of Sciences, China [Y4KF171CJ1] ;  National Natural Science Foundation for Young Scholar of China [11304115] ;  China Postdoctoral Science Foundation [2013M541282]
语种: 英语
Citation statistics: 
内容类型: 期刊论文
URI标识: http://ir.itp.ac.cn/handle/311006/20770
Appears in Collections:理论物理所2015年知识产出_期刊论文

Files in This Item: Download All
File Name/ File Size Content Type Version Access License
Theoretical studies on sRNA-mediated regulation in bacteria.pdf(1279KB)期刊论文出版稿开放获取View Download

Recommended Citation:
Chang, XX,Xu, LF,Shi, HL. Theoretical studies on sRNA-mediated regulation in bacteria[J]. CHINESE PHYSICS B,2015,24(12):128703.
Service
 Recommend this item
 Sava as my favorate item
 Show this item's statistics
 Export Endnote File
Google Scholar
 Similar articles in Google Scholar
 [Chang, XX]'s Articles
 [Xu, LF]'s Articles
 [Shi, HL]'s Articles
CSDL cross search
 Similar articles in CSDL Cross Search
 [Chang, XX]‘s Articles
 [Xu, LF]‘s Articles
 [Shi, HL]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
  Add to CiteULike  Add to Connotea  Add to Del.icio.us  Add to Digg  Add to Reddit 
文件名: Theoretical studies on sRNA-mediated regulation in bacteria.pdf
格式: Adobe PDF
所有评论 (0)
暂无评论
 
评注功能仅针对注册用户开放,请您登录
您对该条目有什么异议,请填写以下表单,管理员会尽快联系您。
内 容:
Email:  *
单位:
验证码:   刷新
您在IR的使用过程中有什么好的想法或者建议可以反馈给我们。
标 题:
 *
内 容:
Email:  *
验证码:   刷新

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Copyright © 2007-2017  中国科学院理论物理研究所 - Feedback
Powered by CSpace