Zeng, Y (reprint author), Guizhou Univ, Coll Civil Engn, Guiyang 550025, Peoples R China.
In colloidal suspensions containing large and small particles, a peculiar attractive force caused by entropy appears, this force can cause aggregation of large particles. With the concentration of small particles increasing, the large particles can be endocytosed by vesicle. A continuum model is developed to investigate the equilibrium mechanics between a biomembrane and an enveloped colloidal particle with different aspect ratios. The results show that the endocytosis of colloidal particle depends on the aspect ratio of colloidal particle. For a spherical colloidal particle (aspect ratio is zero), the entropy provides sufficient favorable energy to drive its engulfment; however, at a high aspect ratio, the entropy is not sufficient to overcome the resistance from the biomembrane and causes endocytosis.
National Natural Science Foundation of China [11047022, 11204045, 31360215]
; Research Foundation from Ministry of Education of China 
; Guizhou provincial tracking key program of social development [SY20123089, SZ20113069]
; Natural Science Foundation of Guizhou Province [J20122166]
; visiting scholar foundation from the key laboratory of biorheological science and technology of ministry of education (Chongqing University)
; research foundation for young university teachers from Guizhou University