Knowledge Management System of Institute of Theoretical Physics, CAS
| A protein structural alphabet and its substitution matrix CLESUM | |
Zheng, WM ; Liu, X
| |
| 2005 | |
| Conference Name | International Workshop on Bioinformatics Research and Applications (IWBRA 2004) |
| Source Publication | TRANSACTIONS ON COMPUTATIONAL SYSTEMS BIOLOGY II |
| Volume | 3680 |
| Pages | 59-67 |
| Conference Date | MAY 22-24, 2005 |
| Conference Place | Emory Univ, Atlanta, GA |
| Author of Source | Emory Univ |
| Publication Place | BERLIN |
| ISSN | 0302-9743 |
| Publisher | SPRINGER-VERLAG BERLIN |
| ISBN | 3-540-29401-5 |
| Abstract | By using a mixture model for the density distribution of the three psendobond angles formed by C-alpha atoms of four consecutive residues, the local structural states are discretized as 17 conformational letters of a protein structural alphabet. This coarse-graining procedure converts a 3D structure to a 1D code sequence. A substitution matrix between these letters is constructed based on the structural alignments of the PSSP database. |
| Keyword | HIDDEN MARKOV MODEL PREDICTION BACKBONE |
| DOI | 10.1109/WOCC.2005.1553741 |
| URL | 查看原文 |
| Indexed By | CPCI |
| Language | 英语 |
| WOS Research Area | Biochemistry & Molecular Biology ; Computer Science |
| WOS Subject | Biochemical Research Methods ; Computer Science, Interdisciplinary Applications ; Computer Science, Theory & Methods |
| Citation statistics | |
| Document Type | 会议论文 |
| Identifier | http://ir.itp.ac.cn/handle/311006/23709 |
| Collection | SCI会议论文 |
| Affiliation | 1.Acad Sinica, Inst Theoret Phys, Beijing 100080, Peoples R China 2.Acad Sinica, Interdisciplinary Ctr Theoret Studies, Beijing 100080, Peoples R China |
| Recommended Citation GB/T 7714 | Zheng, WM,Liu, X. A protein structural alphabet and its substitution matrix CLESUM[C]//Emory Univ. BERLIN:SPRINGER-VERLAG BERLIN,2005:59-67. |
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