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A protein structural alphabet and its substitution matrix CLESUM
Zheng, WM; Liu, X
2005
Conference NameInternational Workshop on Bioinformatics Research and Applications (IWBRA 2004)
Source PublicationTRANSACTIONS ON COMPUTATIONAL SYSTEMS BIOLOGY II
Volume3680
Pages59-67
Conference DateMAY 22-24, 2005
Conference PlaceEmory Univ, Atlanta, GA
Author of SourceEmory Univ
Publication PlaceBERLIN
ISSN0302-9743
PublisherSPRINGER-VERLAG BERLIN
ISBN3-540-29401-5
AbstractBy using a mixture model for the density distribution of the three psendobond angles formed by C-alpha atoms of four consecutive residues, the local structural states are discretized as 17 conformational letters of a protein structural alphabet. This coarse-graining procedure converts a 3D structure to a 1D code sequence. A substitution matrix between these letters is constructed based on the structural alignments of the PSSP database.
KeywordHIDDEN MARKOV MODEL PREDICTION BACKBONE
DOI10.1109/WOCC.2005.1553741
URL查看原文
Indexed ByCPCI
Language英语
WOS Research AreaBiochemistry & Molecular Biology ; Computer Science
WOS SubjectBiochemical Research Methods ; Computer Science, Interdisciplinary Applications ; Computer Science, Theory & Methods
Citation statistics
Cited Times:10[WOS]   [WOS Record]     [Related Records in WOS]
Document Type会议论文
Identifierhttp://ir.itp.ac.cn/handle/311006/23709
CollectionSCI会议论文
Affiliation1.Acad Sinica, Inst Theoret Phys, Beijing 100080, Peoples R China
2.Acad Sinica, Interdisciplinary Ctr Theoret Studies, Beijing 100080, Peoples R China
Recommended Citation
GB/T 7714
Zheng, WM,Liu, X. A protein structural alphabet and its substitution matrix CLESUM[C]//Emory Univ. BERLIN:SPRINGER-VERLAG BERLIN,2005:59-67.
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