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题名: Mechanochemical Coupling of Kinesin Studied with a Neck-Linker Swing Model
作者: Li Ming ;  Shu Yao-Gen ;  Ou-Yang Zhong-Can
刊名: COMMUNICATIONS IN THEORETICAL PHYSICS
出版日期: 2009
卷号: 51, 期号:6, 页码:1143-1148
关键词: HAND-OVER-HAND ;  OPTICAL FORCE CLAMP ;  MOLECULAR MOTORS ;  ATP HYDROLYSIS ;  KINETIC MECHANISM ;  INTERNAL STRAIN ;  MOTILITY ;  STEPS ;  HEAD ;  MICROTUBULE
学科分类: Physics
通讯作者: Shu, YG , Chinese Acad Sci, Inst Theoret Phys, Key Lab Frontiers Theoret Phys, Beijing 100190, Peoples R China
部门归属: [Shu, YG; Ou-Yang, ZC] Chinese Acad Sci, Inst Theoret Phys, Key Lab Frontiers Theoret Phys, Beijing 100190, Peoples R China; [Li, M] Chinese Acad Sci, Grad Univ, Coll Phys Sci, Beijing 100190, Peoples R China
英文摘要: A neck-linker swing model has been proposed in this work to investigate the mechanochemical coupling of kinesin. The difference between force-velocity curves given by force clamp and fixed trap respectively has been satisfactorily interpreted by this model. The study implies that ADP releasing and ATP hydrolysis are much less force-dependent in force clamp experiments than that in fixed trap experiments in the regime of moderate loading force, which might be a consequence of the delayed response of servo system in force clamp experiments.
资助者: National Basic Research Program of China[2007CB935903]
收录类别: SCI
WOS记录号: WOS:000267265700034
Citation statistics: 
内容类型: 期刊论文
URI标识: http://ir.itp.ac.cn/handle/311006/5313
Appears in Collections:理论物理所1978-2010年知识产出_期刊论文

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Recommended Citation:
Li Ming,Shu Yao-Gen,Ou-Yang Zhong-Can. Mechanochemical Coupling of Kinesin Studied with a Neck-Linker Swing Model[J]. COMMUNICATIONS IN THEORETICAL PHYSICS,2009,51(6):1143-1148.
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