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Mechanochemical Coupling of Kinesin Studied with a Neck-Linker Swing Model
Li Ming; Shu Yao-Gen; Ou-Yang Zhong-Can; Shu, YG , Chinese Acad Sci, Inst Theoret Phys, Key Lab Frontiers Theoret Phys, Beijing 100190, Peoples R China
2009
发表期刊COMMUNICATIONS IN THEORETICAL PHYSICS
ISSN0253-6102
卷号51期号:6页码:1143-1148
摘要A neck-linker swing model has been proposed in this work to investigate the mechanochemical coupling of kinesin. The difference between force-velocity curves given by force clamp and fixed trap respectively has been satisfactorily interpreted by this model. The study implies that ADP releasing and ATP hydrolysis are much less force-dependent in force clamp experiments than that in fixed trap experiments in the regime of moderate loading force, which might be a consequence of the delayed response of servo system in force clamp experiments.
部门归属[Shu, YG; Ou-Yang, ZC] Chinese Acad Sci, Inst Theoret Phys, Key Lab Frontiers Theoret Phys, Beijing 100190, Peoples R China; [Li, M] Chinese Acad Sci, Grad Univ, Coll Phys Sci, Beijing 100190, Peoples R China
关键词Hand-over-hand Optical Force Clamp Molecular Motors Atp Hydrolysis Kinetic Mechanism Internal Strain Motility Steps Head Microtubule
学科领域Physics
资助者National Basic Research Program of China[2007CB935903] ; National Basic Research Program of China[2007CB935903] ; National Basic Research Program of China[2007CB935903] ; National Basic Research Program of China[2007CB935903]
收录类别SCI
资助者National Basic Research Program of China[2007CB935903] ; National Basic Research Program of China[2007CB935903] ; National Basic Research Program of China[2007CB935903] ; National Basic Research Program of China[2007CB935903]
WOS记录号WOS:000267265700034
引用统计
被引频次:3[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.itp.ac.cn/handle/311006/5313
专题1978-2010年知识产出
通讯作者Shu, YG , Chinese Acad Sci, Inst Theoret Phys, Key Lab Frontiers Theoret Phys, Beijing 100190, Peoples R China
推荐引用方式
GB/T 7714
Li Ming,Shu Yao-Gen,Ou-Yang Zhong-Can,et al. Mechanochemical Coupling of Kinesin Studied with a Neck-Linker Swing Model[J]. COMMUNICATIONS IN THEORETICAL PHYSICS,2009,51(6):1143-1148.
APA Li Ming,Shu Yao-Gen,Ou-Yang Zhong-Can,&Shu, YG , Chinese Acad Sci, Inst Theoret Phys, Key Lab Frontiers Theoret Phys, Beijing 100190, Peoples R China.(2009).Mechanochemical Coupling of Kinesin Studied with a Neck-Linker Swing Model.COMMUNICATIONS IN THEORETICAL PHYSICS,51(6),1143-1148.
MLA Li Ming,et al."Mechanochemical Coupling of Kinesin Studied with a Neck-Linker Swing Model".COMMUNICATIONS IN THEORETICAL PHYSICS 51.6(2009):1143-1148.
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