Systematic Kinetics Study of FoF1-ATPase: Analytic Results and Comparison with Experiments

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	Shu, Yao-Gen; Lai, Pik-Yin; Shu, YG , Natl Cent Univ, Grad Inst Biophys, Dept Phys, Chungli 320, Taiwan
	Systematic Kinetics Study of FoF1-ATPase: Analytic Results and Comparison with Experiments
发表期刊	JOURNAL OF PHYSICAL CHEMISTRY B
关键词	3 Catalytic Sites Bovine Heart-mitochondria Atp Synthase Catalysis Escherichia-coli Substrate-binding Molecular Motors Proton-transport Oxidative-phosphorylation Energy Transduction F1f0-atp Synthase
摘要	The systematic kinetics of the holoenzyme FoF1-ATPase has been investigated by a tri-site filled, random binding order, and stochastic mechanochemical tight coupling model. The connection between the mechanical rotation speed and the chemical quantities such as the concentrations of substrates, the proton motive force, and the mechanical damping coefficient, has been analytically derived. The enzymatics based on ensemble experiments and single-molecule assays can be discussed systematically. Our model predictions agree well with both ensemble and single-molecule experimental results. Furthermore, this model can be used to study the dynamics of FoF1-ATPase in a vesicle system.
	2008
ISSN	1520-6106
卷号	112 期号:42 页码:13453-13459
学科领域	Physics
收录类别	SCI
项目资助者	NSC[NSC 96-2112-M008-023]; National Center for Theoretical Sciences of Taiwan ; NSC[NSC 96-2112-M008-023]; National Center for Theoretical Sciences of Taiwan ; NSC[NSC 96-2112-M008-023]; National Center for Theoretical Sciences of Taiwan ; NSC[NSC 96-2112-M008-023]; National Center for Theoretical Sciences of Taiwan
引用统计	被引频次：13[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.itp.ac.cn/handle/311006/5447
专题	理论物理所科研产出_SCI论文
通讯作者	Shu, YG , Natl Cent Univ, Grad Inst Biophys, Dept Phys, Chungli 320, Taiwan
推荐引用方式 GB/T 7714	Shu, Yao-Gen,Lai, Pik-Yin,Shu, YG , Natl Cent Univ, Grad Inst Biophys, Dept Phys, Chungli 320, Taiwan. Systematic Kinetics Study of FoF1-ATPase: Analytic Results and Comparison with Experiments[J]. JOURNAL OF PHYSICAL CHEMISTRY B,2008,112(42):13453-13459.
APA	Shu, Yao-Gen,Lai, Pik-Yin,&Shu, YG , Natl Cent Univ, Grad Inst Biophys, Dept Phys, Chungli 320, Taiwan.(2008).Systematic Kinetics Study of FoF1-ATPase: Analytic Results and Comparison with Experiments.JOURNAL OF PHYSICAL CHEMISTRY B,112(42),13453-13459.
MLA	Shu, Yao-Gen,et al."Systematic Kinetics Study of FoF1-ATPase: Analytic Results and Comparison with Experiments".JOURNAL OF PHYSICAL CHEMISTRY B 112.42(2008):13453-13459.

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