Knowledge Management System of Institute of Theoretical Physics, CAS
| Shu, Yao-Gen; Lai, Pik-Yin; Shu, YG , Natl Cent Univ, Grad Inst Biophys, Dept Phys, Chungli 320, Taiwan | |
| Systematic Kinetics Study of FoF1-ATPase: Analytic Results and Comparison with Experiments | |
| Source Publication | JOURNAL OF PHYSICAL CHEMISTRY B
 |
| Keyword | 3 Catalytic Sites Bovine Heart-mitochondria Atp Synthase Catalysis Escherichia-coli Substrate-binding Molecular Motors Proton-transport Oxidative-phosphorylation Energy Transduction F1f0-atp Synthase |
| Abstract | The systematic kinetics of the holoenzyme FoF1-ATPase has been investigated by a tri-site filled, random binding order, and stochastic mechanochemical tight coupling model. The connection between the mechanical rotation speed and the chemical quantities such as the concentrations of substrates, the proton motive force, and the mechanical damping coefficient, has been analytically derived. The enzymatics based on ensemble experiments and single-molecule assays can be discussed systematically. Our model predictions agree well with both ensemble and single-molecule experimental results. Furthermore, this model can be used to study the dynamics of FoF1-ATPase in a vesicle system. |
| 2008 | |
| ISSN | 1520-6106 |
| Volume | 112Issue:42Pages:13453-13459 |
| Subject Area | Physics |
| Indexed By | SCI |
| Funding Organization | NSC[NSC 96-2112-M008-023]; National Center for Theoretical Sciences of Taiwan ; NSC[NSC 96-2112-M008-023]; National Center for Theoretical Sciences of Taiwan ; NSC[NSC 96-2112-M008-023]; National Center for Theoretical Sciences of Taiwan ; NSC[NSC 96-2112-M008-023]; National Center for Theoretical Sciences of Taiwan |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.itp.ac.cn/handle/311006/5447 |
| Collection | SCI期刊论文 |
| Corresponding Author | Shu, YG , Natl Cent Univ, Grad Inst Biophys, Dept Phys, Chungli 320, Taiwan |
| Recommended Citation GB/T 7714 | Shu, Yao-Gen,Lai, Pik-Yin,Shu, YG , Natl Cent Univ, Grad Inst Biophys, Dept Phys, Chungli 320, Taiwan. Systematic Kinetics Study of FoF1-ATPase: Analytic Results and Comparison with Experiments[J]. JOURNAL OF PHYSICAL CHEMISTRY B,2008,112(42):13453-13459. |
| APA | Shu, Yao-Gen,Lai, Pik-Yin,&Shu, YG , Natl Cent Univ, Grad Inst Biophys, Dept Phys, Chungli 320, Taiwan.(2008).Systematic Kinetics Study of FoF1-ATPase: Analytic Results and Comparison with Experiments.JOURNAL OF PHYSICAL CHEMISTRY B,112(42),13453-13459. |
| MLA | Shu, Yao-Gen,et al."Systematic Kinetics Study of FoF1-ATPase: Analytic Results and Comparison with Experiments".JOURNAL OF PHYSICAL CHEMISTRY B 112.42(2008):13453-13459. |
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| Systematic Kinetics （1141KB） | 开放获取 | License | Application Full Text | |||
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