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题名: TreeFam: a curated database of phylogenetic trees of animal gene families
作者: Li, Heng ;  Coghlan, Avril ;  Ruan, Jue ;  Coin, Lachlan James ;  Heriche, Jean-Karim ;  Osmotherly, Lara ;  Li, Ruiqiang ;  Liu, Tao ;  Zhang, Zhang ;  Bolund, Lars ;  Wong, Gane Ka-Shu ;  Zheng, Weimou ;  Dehal, Paramvir ;  Wang, Jun ;  Durbin, Richard
刊名: NUCLEIC ACIDS RESEARCH
出版日期: 2006
卷号: 34, 期号:34, 页码:D572-D580
关键词: PROTEIN FAMILIES ;  MULTIGENE FAMILY ;  GENOME ;  ORTHOLOGS ;  PHYLOGENOMICS ;  PARALOGS ;  DUPLICATION ;  VERTEBRATE ;  RESOURCES ;  EVOLUTION
学科分类: Physics
通讯作者: Durbin, R , Wellcome Trust Sanger Inst, Wellcome Trust Genome Campus, Cambridge CB10 1SA, England
部门归属: Wellcome Trust Sanger Inst, Cambridge CB10 1SA, England; Chinese Acad Sci, Beijing Inst Gen, Beijing Gen Inst, Beijing 101300, Peoples R China; Chinese Acad Sci, Inst Theoret Phys, Beijing 100080, Peoples R China; Univ Aarhus, Inst Human Genet, DK-8000 Aarhus C, Denmark; Univ So Denmark, Dept Biochem & Mol Biol, DK-5230 Odense M, Denmark; Chinese Acad Sci, Inst Comp Technol, Beijing 100080, Peoples R China; Univ Washington, Dept Med, Genome Ctr, Seattle, WA 98195 USA; Joint Genome Inst, Evolutionary Gen Dept, Dept Energy, Walnut Creek, CA USA; Lawrence Berkeley Lab, Walnut Creek, CA USA
英文摘要: TreeFam is a database of phylogenetic trees of gene families found in animals. It aims to develop a curated resource that presents the accurate evolutionary history of all animal gene families, as well as reliable ortholog and paralog assignments. Curated families are being added progressively, based on seed alignments and trees in a similar fashion to Pfam. Release 1.1 of TreeFam contains curated trees for 690 families 25 and automatically generated trees for another 11 646 families. These represent over 128 000 genes from nine fully sequenced animal genomes and over 45 000 other animal proteins from UniProt; similar to 40 - 85% of proteins encoded in the fully sequenced animal genomes are included in TreeFam. TreeFam is freely available at http://www.treefam.org and http://treefam.genomics.org.cn.
收录类别: SCI
原文出处: 查看原文
WOS记录号: WOS:000239307700123
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内容类型: 期刊论文
URI标识: http://ir.itp.ac.cn/handle/311006/6068
Appears in Collections:理论物理所1978-2010年知识产出_期刊论文

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Recommended Citation:
Li, Heng,Coghlan, Avril,Ruan, Jue,et al. TreeFam: a curated database of phylogenetic trees of animal gene families[J]. NUCLEIC ACIDS RESEARCH,2006,34(34):D572-D580.
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