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A Decrease in Transcription Capacity Limits Growth Rate upon Translation Inhibition 期刊论文
MSYSTEMS, 2020, 卷号: 5, 期号: 5, 页码: e00575-20
Authors:  Zhang, Qing;  Brambilla, Elisa;  Li, Rui;  Shi, Hualin;  Lagomarsino, Marco Cosentino;  Sclavi, Bianca
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RNA-POLYMERASE AVAILABILITY  ESCHERICHIA-COLI  RIBOSOMAL-RNA  GENE-EXPRESSION  PPGPP  EFFICIENCY  PROMOTERS  SUBUNITS  (P)PPGPP  REVEALS  
Optimal Allocation of Bacterial Protein Resources under Nonlethal Protein Maturation Stress 期刊论文
BIOPHYSICAL JOURNAL, 2018, 卷号: 115, 期号: 5, 页码: 896-910
Authors:  Zhang, Q;  Li, R;  Li, JB;  Shi, HL
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ESCHERICHIA-COLI PROTEOME  SIGMA-FACTOR COMPETITION  GENE-EXPRESSION  RNA-POLYMERASE  OXIDATIVE STRESS  GROWTH-INHIBITION  CELL-GROWTH  TRANSLATION  RATES  OVERPRODUCTION  
Molecular dynamics simulation study of the "stay or leave" problem for two magnesium ions in gene transcription 期刊论文
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 2017, 卷号: 85, 期号: 6, 页码: 1002-1007
Authors:  Wu, SG;  Wu, SG (reprint author), Sichuan Normal Univ, Coll Chem & Mat Sci, Chengdu 610066, Peoples R China.
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Molecular Dynamics Simulation  T7 Rna Polymerase  Magnesium Ion  Transcription Mechanism  Free Energy  
Mechanism of NTP Binding to the Active Site of T7 RNA Polymerase Revealed by Free-Energy Simulation 期刊论文
BIOPHYSICAL JOURNAL, 2017, 卷号: 112, 期号: 11, 页码: 2253-2260
Authors:  Wu, SG;  Li, LC;  Li, Q;  Wu, SG (reprint author), Sichuan Normal Univ, Coll Chem & Mat Sci, Chengdu, Peoples R China.;  Wu, SG (reprint author), Chinese Acad Sci, Inst Theoret Phys, State Key Lab Theoret Phys, Beijing, Peoples R China.
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Proofreading of DNA polymerase: a new kinetic model with higher-order terminal effects 期刊论文
JOURNAL OF PHYSICS-CONDENSED MATTER, 2017, 卷号: 29, 期号: 2, 页码: 25101
Authors:  Song, YS;  Shu, YG;  Zhou, X;  Ou-Yang, ZC;  Li, M;  Li, M (reprint author), Univ Chinese Acad Sci, Sch Phys Sci, 19A Yuquan Rd, Beijing 100049, Peoples R China.
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Dna Polymerase  Proofreading  Kinetics  Fidelity  Higher-order Terminal Effects  
Mechanism of pyrophosphate ion release in T7 RNA polymerase revealed by free energy simulations 期刊论文
COMPUTATIONAL AND THEORETICAL CHEMISTRY, 2016, 卷号: 1094, 页码: 127-132
Authors:  Wu, SG;  Jiang, MQ;  Liu, L;  Wu, SG (reprint author), Sichuan Normal Univ, Coll Chem & Mat Sci, Chengdu 610068, Peoples R China.
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Molecular Dynamics Simulation  T7 Rna Polymerase  Ppi Release  Potential Of Mean Force  
Effects of cooperation between translating ribosome and RNA polymerase on termination efficiency of the Rho-independent terminator 期刊论文
NUCLEIC ACIDS RESEARCH, 2016, 卷号: 44, 期号: 6, 页码: 2554-2563
Authors:  Li, R;  Zhang, Q;  Li, JB;  Shi, HL;  Shi, HL (reprint author), Chinese Acad Sci, Inst Theoret Phys, State Key Lab Theoret Phys, Beijing 100190, Peoples R China.;  Li, JB (reprint author), Chinese Acad Sci, Inst Chem, Beijing 100190, Peoples R China.;  Li, JB (reprint author), Natl Ctr Nanosci & Technol, Beijing 100190, Peoples R China.
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Conditional entropy in variation-adjusted windows detects selection signatures associated with expression quantitative trait loci (eQTLs) 期刊论文
BMC GENOMICS, 2015, 卷号: 16, 期号: 0, 页码: S8
Authors:  Handelman, SK;  Seweryn, M;  Smith, RM;  Hartmann, K;  Wang, DX;  Pietrzak, M;  Johnson, AD;  Kloczkowski, A;  Sadee, W;  Handelman, SK (reprint author), Ohio State Univ, Coll Med, Ctr Pharmacogen, Graves Hall,330 W 10th Ave, Columbus, OH 43210 USA.
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F-1-ATPase Stabilizes and Positions Adenosine Triphosphate Revealed by Molecular Dynamics Simulations 期刊论文
ACTA PHYSICO-CHIMICA SINICA, 2015, 卷号: 31, 期号: 9, 页码: 1803-1809
Authors:  Wu, SG;  Gao, XT;  Li, Q;  Liao, J;  Xu, CG;  Wu, SG (reprint author), Sichuan Normal Univ, Coll Chem & Mat Sci, Chengdu 610068, Peoples R China.
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F-1-atpase  Hydrogen Bond  Molecular Dynamics  Mutation  
Strategy of tuning gene expression ratio in prokaryotic cell from perspective of noise and correlation 期刊论文
JOURNAL OF THEORETICAL BIOLOGY, 2015, 卷号: 365, 期号: 0, 页码: 377-389
Authors:  Li, R;  Xu, LF;  Shi, HL;  Shi, HL (reprint author), Chinese Acad Sci, Inst Theoret Phys, State Key Lab Theoret Phys, Beijing 100190, Peoples R China.
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Polar Effect  The Two-state Promoter  Transcription Terminator  Gene Expression Correlation  Operon Structure